NFL Week 3's schedule serves up several high-powered matchups, but the most intriguing game might between the Cowboys and Ravens.

Last week was chaos with upsets galore, and only one of our staffers was above .500 with their game picks (the other five all went exactly 8–8). So should we expect more of the same this week? There are a few games where multiple writers or editors predict an upset.

If the Chargers can beat the Steelers in Pittsburgh, Los Angeles would be undefeated when it plays host to the two-time defending champion Chiefs next week.

A suspenseful set of standalone, primetime games through two weeks has served as a reminder to why the NFL reigns supreme in popularity — and of how difficult it can be bet on.

It was a solid Week 2 for me -- at least against the spread. You would think I'd be better picking the games straight up, but that wasn't the case last week. I went 7-9 straight up for a 17-15 overall record and I was 9-6-1 ATS for a 17-12-3 record.

Newsweek's sports betting analysts tackle every Week 3 game, including the Monday Night Football doubleheader of Jaguars-Bills and Commanders-Bengals.