Sunday, 4:25 p.m. EDT, FOX BetMGM NFL odds: 49ers by 7 1/2. Against the spread: 49ers 1-1; Rams 0-2. Series record: 49ers lead 78-69-3. Last meeting: Rams beat 49ers 21-20 in Santa Clara, Calif. on Jan.

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have still been must-see spectacles

The Rams have their work cut out for them in Week 3 but they have a chance to upset the 49ers if they win these 5 matchups

In his professional career, Cephus has recorded 37 receptions for 568 yards and four touchdowns across 22 games. As the Rams navigate the challenges brought on by injuries to two key players, Cephus will aim to play a pivotal role in revitalizing an offense in need of depth and playmaking abilities.

With Puka Nacua and Cooper Kupp out, the Rams are bringing in a wide receiver who’s played with Matthew Stafford before

The Los Angeles Rams have not put receiver Cooper Kupp on IR as they are hoping for a short recovery time from his ankle injury.

Injuries have turned what was a promising Rams roster into one that could struggle to make the playoffs. The offensive line has been decimated and the receiving corps is now taking a major hit with Puka Nacua and Cooper Kupp out several weeks.